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A high extracellular glutamate concentration was one of the first xCT inhibitors described but a few years later, erastin (standing for eradicator of RAS and small T antigen-expressing cells) was identified by Stockwell's group in RAS-mutated cancer cell lines as inhibitor of xCT transport (42)
J Physiol Pharmacol 60:191196 Brooks J (2005) Epidemiology of injuries in English professional rugby union: part 2 training injuries
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